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Dept. Biochemistry & Molecular Biology

Chapman Teaching


CON 668: Molecular Biophysics & Experimental Bioinformatics

Introduction to Macromolecular X-ray crystallography (2 lectures):

teaching/con668/X-ray Crystallography.pdf

CON 605: PMCB Journal Club

Fatty Acid Synthase (2 meetings; Fall 2008):

teaching/con605/Fatty Acid Synthase handout.pdf

Structure & Activity of tuberculosis Toxin/Anti-toxin systems (2 meetings; Fall 2009):

Background (PowerPoint)

Lewis & Clark College: HHMI Workshop

Macromolecular Crystallography - October / November 2009

Week

Topics

Practicals

1

Introduction (PowerPoint) (PDF handout);

Crystallization (PowerPoint) (PDF handout)

Lysozyme crystallization lab (PDF)

2

Diffraction theory & Data collection (PowerPoint) (PDF handout)

 

3

The Phase Problem (PowerPoint) (PDF handout)

 

4

Modeling, Refinement, Accuracy & Validation (PowerPoint) (PDF handout)

Building with computer graphics (Modeling_tutorial.htm)